Taula de Continguts
What Are Polynucleotides?
Polynucleotides are naturally occurring molecules, extracted from purified sources, that act as biostimulators. Their main function is to activate the skin's cellular regeneration processes. By doing so, they improve the intrinsic quality of the skin tissue, promoting a healthier and more rejuvenated appearance.
This approach is distinguished by its action from within, encouraging the natural production of collagen and elastin. They do not aim for an immediate filling effect, but rather a progressive and lasting improvement in dermal structure. It is a treatment that respects the skin's physiology.
How Do Polynucleotides Work in the Skin?
Once injected, polynucleotides act on several levels to restore skin health. First, they have a powerful hydrating action, attracting and retaining water molecules to improve turgor. Second, they neutralize free radicals, protecting cells from oxidative damage.
Finally, and crucially, they stimulate fibroblasts, the cells responsible for producing collagen and elastin. This biostimulation leads to firmer, more elastic, and more radiant skin. Results are gradual and become apparent as the skin regenerates.
Who Are Polynucleotides Indicated For?
Polynucleotides are a suitable option for people who want to improve their skin quality naturally. They are recommended for those who show signs of aging such as mild sagging, loss of elasticity, dullness, or dehydration. They are also useful for preventing premature aging.
This treatment is versatile and can be applied to various areas. It is particularly effective on the face, neck, décolletage, and the delicate under-eye area.
Common Application Areas
The regenerative capacity of polynucleotides makes them ideal for treating multiple areas. Their application extends beyond the face, covering areas where the skin is thin and vulnerable. Results vary depending on the area and the individual characteristics of each patient.
| Application Area | Expected Benefits |
|---|---|
| Face | Improved elasticity, firmness, reduction of fine lines, and overall radiance. |
| Under-Eye Area (Dark Circles) | Reduction of pigmentation and improvement of thin skin quality, reducing the tired appearance. |
| Neck and Décolletage | Reduction of wrinkles, improvement of sagging, and increased hydration. |
The Treatment Process: What to Expect?
Treatment with polynucleotides is performed through microinjections into the superficial layers of the skin. Before any procedure, a thorough medical evaluation is carried out to ensure the suitability of the treatment. A topical anesthetic cream is applied to minimize any discomfort.
The board-certified doctor carefully injects the product into strategic points in the area to be treated. The duration of the session is usually about 30 to 45 minutes. After the treatment, small red spots or swelling may appear, which generally disappear within a few hours or the next day.
The usual protocol includes several sessions, spaced every 2 to 4 weeks, depending on the medical evaluation. The results are progressive and manifest as the skin responds to biostimulation. It is essential to follow post-treatment instructions to optimize results.
Key Points
- Polynucleotides are biostimulators that promote cellular regeneration.
- They naturally improve skin hydration, elasticity, and radiance.
- They are applied through microinjections to the face, neck, décolletage, and under-eye area.
- The treatment requires several sessions for optimal results.
- It is an option for preventing and treating mild signs of aging.
How Santé Clínica Estética Approaches It
At Santé Clínica Estética, the application of polynucleotides is a medical procedure that we perform with the utmost precision and safety. Our team of board-certified doctors, led by Dr. Sol Monsalve, evaluates each case individually. We consider your medical history, your skin characteristics, and your expectations.
The aesthetic consultation is free and is offered in Spanish, English, Portuguese, and Russian, facilitating communication. In this first appointment, a personalized protocol is designed that may include polynucleotides as part of a comprehensive plan. The injection technique is ultrasound-guided when anatomy requires it, which increases safety and precision.
Our commitment is to offer natural results that enhance your beauty without transforming it. Transparency is key: you will be informed in detail about the process, possible side effects, and the price of the treatment. Your well-being and achieving a harmonious result are our priority.
"Skin regeneration does not seek to change who you are, but to restore what time may have diminished. Polynucleotides offer a way for your own skin to strengthen and look more vital, in a very subtle and progressive way." – Dr. Sol Monsalve, Medical Director of Santé Clínica Estética.
Frequently Asked Questions
Are the results immediate?
No, the results of polynucleotides are gradual. Cellular regeneration is a biological process that takes time. Generally, improvements in skin quality begin to be noticed 2-4 weeks after the first session, with more evident results after completing the recommended protocol.
Is the treatment painful?
Most patients experience minimal discomfort during the treatment. Before the injections, we apply a topical anesthetic cream to ensure your comfort. The needles used are very fine, and the experience of our medical team contributes to making the procedure as tolerable as possible.
How many sessions are needed?
The number of sessions varies depending on the initial skin condition and the patient's goals. Typically, a protocol of 3 to 4 sessions is recommended, spaced every 2 to 4 weeks. Subsequently, maintenance sessions can be performed every 6-12 months to prolong the effects. Your doctor will establish the most suitable plan for you.
What is the price of polynucleotides at Santé Clínica Estética?
At Santé Clínica Estética, the price of a facial polynucleotide session is 400€. We offer a pack of 3 sessions for 1,000€. For the under-eye area, the price is also 400€ per session, and a pack of 3 sessions for 1,000€. Polynucleotides for the neck or décolletage are priced at 400€ per session. These prices may vary depending on the area and the specific protocol established during your medical consultation.
Are there any contraindications?
Yes, as with any medical treatment, there are contraindications. The use of polynucleotides is not recommended for pregnant or breastfeeding women, people with active skin infections in the treatment area, severe autoimmune diseases, or known allergies to any of the components. Your doctor will perform a complete evaluation to rule out any risks.
- Free Consultation and Medical Evaluation
- Is the Treatment Suitable?
- Personalized Protocol Design
- Application of Topical Anesthesia
- Polynucleotide Microinjections by Board-Certified Doctor
- Post-Treatment Recommendations
- Successive Sessions (according to protocol)
- Results Evaluation and Maintenance
- Exploration of Alternatives or Referral

