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Plasma Gel: Natural Filler with Your Own Blood

Plasma gel is an autologous dermal filler, meaning it is derived from the patient's own blood. This gel is used to restore facial volume and improve skin quality naturally.

September 27, 2026
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What is plasma gel and how does it work?

Plasma gel is a dermal filler material made from the patient's own blood plasma. This process involves extracting a small blood sample, similar to a routine blood test. Subsequently, this blood is centrifuged to separate the platelet-rich plasma (PRP), which is then subjected to a controlled heating and cooling process to transform it into a gel.

Once obtained, this autologous gel is injected into the desired areas to restore volume, fill wrinkles, or improve skin texture. As it is a product derived from the body itself, the risk of allergic reactions or rejection is minimal. Its effects are temporary, as the body gradually reabsorbs it.

Who is plasma gel indicated for?

Plasma gel is an option for patients seeking aesthetic improvement with a natural approach. It is particularly indicated for those who wish to restore lost facial volume, fill fine or moderate wrinkles, or improve overall skin quality. It is an alternative for those who prefer to avoid synthetic materials.

The desired results are a fresher and more rejuvenated appearance, maintaining the naturalness of the features. It is suitable for people who want a treatment with a high safety profile, as it uses components from their own body. Prior medical evaluation is essential to determine the suitability of the treatment.

What areas can be treated with plasma gel?

Plasma gel can be applied to various areas of the face and, occasionally, to other body areas to restore volume and improve the skin. The most common areas include the cheekbones, nasolabial folds, marionette lines, and chin. It can also be used to improve the appearance of certain wrinkles.

At Santé Clínica Estética, our doctors evaluate each case individually to determine the most suitable areas for treatment. The goal is to achieve facial harmonisation and a rejuvenated appearance without altering natural expression. Application must be performed by qualified medical professionals.

The treatment process: step by step

Plasma gel treatment at Santé Clínica Estética follows a rigorous medical protocol to ensure safety and efficacy. The process is detailed below:

Plasma gel treatment process flow diagram
  1. Free Aesthetic Consultation
  2. Medical Evaluation
  3. Blood Draw
  4. Plasma Gel Preparation
  5. Plasma Gel Application
  6. Post-treatment Instructions
  7. Review (if necessary)
  8. Recommendation of alternatives or referral
  1. Initial aesthetic consultation: The patient's medical history and expectations are evaluated. Details of the procedure are explained, and questions are answered.
  2. Blood draw: A small amount of blood is drawn from the patient's arm, similar to a routine test.
  3. Plasma gel preparation: The blood is centrifuged to separate the plasma. This plasma is processed using a heating and cooling system to convert it into a gel.
  4. Plasma gel application: The doctor injects the plasma gel into the previously agreed-upon areas, using precise techniques to achieve a natural result.
  5. Post-treatment instructions: Indications for aftercare are provided, and a review is scheduled if necessary.

What results can I expect and how long do they last?

Plasma gel results aim for a gradual and natural improvement in appearance. Patients may notice an increase in volume in the treated areas and an improvement in skin texture and elasticity. The effect is a fresher and more rested look, without drastic changes.

The duration of the plasma gel effect is temporary, as the body reabsorbs it over time. Generally, results can last between 3 and 6 months, although this varies depending on each person's metabolism and the treated area. To maintain results, maintenance sessions may be recommended.

Recovery and side effects

After plasma gel treatment, recovery is usually quick with minimal discomfort. It is common to experience slight redness, swelling, or some small bruising in the injection areas. These effects are usually temporary and disappear within a few days.

It is recommended to avoid direct sun exposure, intense exercise, and alcohol consumption during the first 24-48 hours. Our doctors provide detailed instructions for post-treatment care and are available to answer any questions. Individual results may vary.

Prices of treatments at Santé Clínica Estética

At Santé Clínica Estética, price transparency is fundamental. The cost of treatments adapts to the needs of each patient and the areas to be treated. To know the exact price of your personalized plan, we invite you to a free aesthetic consultation.

Key points

  • Plasma gel is an autologous filler derived from the patient's own blood.
  • It is used to restore facial volume and improve skin quality.
  • Results are natural and temporary, lasting 3 to 6 months.
  • The risk of allergic reactions is minimal as it is a product of the body itself.
  • Recovery is generally quick, with mild and transient side effects.
  • The initial aesthetic consultation is free to assess suitability and design a plan.

How Santé Clínica Estética approaches it

At Santé Clínica Estética, we understand that each patient is unique and has specific needs. Therefore, our approach with plasma gel is based on a comprehensive medical evaluation and the creation of a completely personalized protocol. Our team of board-certified doctors, with Dr. Sol Monsalve as Medical Director, guarantees the highest standards of quality and safety in every procedure.

Before any treatment, we offer a free aesthetic consultation. During this consultation, our specialists will evaluate your history, your expectations, and explain in detail the process, realistic results, and aftercare. We firmly believe in the importance of clear and transparent communication, ensuring that every decision is made in an informed and conscious manner.

Our priority is to achieve natural results that enhance your beauty without altering your expression. We use precise application techniques to ensure facial harmony and a rejuvenated appearance. We are committed to your well-being and satisfaction, offering care in Spanish, English, Portuguese, and Russian to adapt to our diverse community of patients in Barcelona.

Frequently asked questions

Is plasma gel painful?

Plasma gel treatment is generally well tolerated. Before injections, a topical anesthetic cream can be applied to minimize any discomfort. Patients usually describe a feeling of pressure or a slight prick during the procedure.

Are there any contraindications for plasma gel?

Yes, there are some contraindications. Treatment is not recommended for patients with coagulation disorders, active infections in the treatment area, severe autoimmune diseases, or cancer. A prior medical evaluation is essential to rule out any risks.

How many plasma gel sessions are needed?

The number of sessions needed varies according to the patient's goals and individual response to treatment. Generally, an initial series of 2 to 3 sessions, spaced over time, may be recommended to optimize results. Maintenance sessions are usually annual or semi-annual.

Can I combine plasma gel with other treatments?

Yes, plasma gel can be combined with other aesthetic treatments to enhance results and address different concerns. For example, it can be complemented with neuromodulators for expression lines or with laser treatments to improve skin quality. The combination of treatments must always be supervised by a specialist doctor.

Generalitat de Catalunya - Departament de Salut - Direcció General d'Ordenació i Regulació SanitàriaFinanciado por la Unión Europea - NextGenerationEU, Gobierno de España, ENISA, Plan de Recuperación, Transformación y Resiliencia