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Polynucleotides and 'Salmon Sperm': The Scientific Truth in Aesthetic Medicine
In the field of aesthetic medicine, it is common to hear terms that, although striking, can cause confusion. One of these is the reference to 'salmon sperm' in relation to polynucleotide treatments. At Santé Clínica Estética, our board-certified doctors wish to clarify this concept and explain what polynucleotides really are and how they benefit your skin's health.
Polynucleotides are biological molecules extracted from sources such as salmon DNA, hence the popular name. These molecules have the ability to stimulate cell regeneration and collagen production in the skin. Their main function is to improve skin quality and health at a deep level, promoting natural recovery and a healthier appearance.
How do polynucleotides work in the skin?
When applied to the skin through microinjections, polynucleotides exert a biostimulating and repairing action. They work by stimulating fibroblasts, the cells responsible for producing collagen and elastin, essential components for firm and youthful skin. They also have antioxidant and anti-inflammatory properties that contribute to overall skin health.
This biostimulation process leads to a progressive improvement in skin texture, tone, and luminosity. In addition, they contribute to deep and long-lasting hydration. Results are observed gradually as the skin regenerates from within, always aiming for a natural and harmonious effect.
Aesthetic applications of polynucleotides
Polynucleotides are used to address various aesthetic concerns, always under the supervision of our doctors. They are especially effective in areas with thin and delicate skin or where a general improvement in skin quality is sought.
- Facial rejuvenation: Improve elasticity, reduce fine lines, and provide luminosity.
- Eye contour: Help to diminish dark circles and improve periorbital skin.
- Neck and décolletage: Revitalize the skin in these areas, often exposed to aging.
- Hands: Contribute to the hydration and rejuvenation of the skin on the hands.
Polynucleotide treatment: What to expect?
Polynucleotide treatment is performed through microinjections in the area to be treated, always by a board-certified medical professional. The procedure is generally well-tolerated, and topical anesthesia can be applied to minimize any discomfort.
After the session, it is common to observe slight redness or small bruises at the injection points, which usually disappear within a few days. It is recommended to avoid direct sun exposure and intense exercise during the first 24-48 hours. Results are not immediate but develop progressively over several weeks as the skin regenerates.
Protocol and expected results
The usual protocol typically consists of several sessions, spaced between 2 and 4 weeks, depending on the skin condition and individual goals. An aesthetic doctor will determine the exact number of sessions needed after an initial assessment.
The duration of the effects can vary depending on the patient and their lifestyle, but generally last between 6 and 12 months. To prolong the results, periodic maintenance sessions may be recommended. It is crucial to understand that polynucleotides aim for an improvement in skin quality, not a volumetric filling effect.
- Initial Medical Consultation
- Skin and Goals Assessment
- Personalized Protocol Design
- Topical Anesthesia Application (if necessary)
- Polynucleotide Microinjections
- Post-Treatment Care
- Follow-up Sessions (2-4 weeks later)
- Results Evaluation and Maintenance
| Aspect | Treatment Description | Typical Results |
|---|---|---|
| Origin | Biological molecules extracted (e.g., salmon DNA) | Natural biostimulation |
| Mechanism | Stimulation of fibroblasts, collagen and elastin production | Progressive improvement in skin quality |
| Application areas | Face, eye contour, neck, décolletage, hands | More elastic, hydrated, and luminous skin |
| Number of sessions | Generally 2-4 sessions, spaced 2-4 weeks | Depends on individual medical assessment |
| Duration of effects | 6-12 months, with maintenance sessions | Variable depending on the patient |
| Price per session | From 400€ (pack of 3 sessions from 1,000€) | Varies according to area and protocol |
Key points
- Polynucleotides are biostimulators that improve skin quality.
- Their origin in salmon DNA is a distinctive characteristic.
- They stimulate the natural production of collagen and elastin.
- They improve skin hydration, elasticity, and luminosity.
- They are applied through microinjections, with a protocol of several sessions.
- The results are gradual and aim for a natural and healthy appearance.
- At Santé, their application is always performed by board-certified doctors.
A study published in the Journal of Cosmetic Dermatology in 2021 (Lee, S. H., et al.) evaluated the efficacy and safety of polynucleotides for skin rejuvenation. The results showed a significant improvement in skin elasticity of 18.5% and hydration of 15.2% after 12 weeks of treatment, with a favorable safety profile. These data support the use of polynucleotides as an effective option for skin biostimulation.
How Santé Clínica Estética approaches it
At Santé Clínica Estética, we understand that every skin is unique. Therefore, before any polynucleotide treatment, our board-certified doctors conduct a thorough medical assessment. This initial consultation allows us to understand your needs and expectations, ensuring that the treatment is the most suitable for you.
We design a personalized protocol, which may include combining with other techniques if the doctor deems it appropriate, always with the aim of optimizing results safely and naturally. Our professionals will explain the procedure, aftercare, and expected results in detail, always maintaining transparency.
We offer a free aesthetic consultation so you can resolve all your doubts without obligation. In addition, our team is prepared to assist you in Spanish, English, Portuguese, and Russian, facilitating communication for all our patients.
Frequently asked questions
Are polynucleotides safe?
Yes, polynucleotides are considered safe when applied by qualified medical professionals. It is a biocompatible and biodegradable product, which reduces the risk of adverse reactions. As with any injectable, small bruises or temporary redness may appear.
Is polynucleotide treatment painful?
The treatment is performed with very fine needles and, in most cases, a topical anesthetic cream is applied before the injections. This minimizes discomfort, which is usually mild and tolerable. The sensation is similar to that of other facial mesotherapy treatments.
How long do polynucleotide results take to appear?
The results of polynucleotides are not immediate, as the treatment stimulates the natural regeneration of the skin. Improvements in texture, elasticity, and hydration begin to be visible 2-4 weeks after the first session and continue to progress with subsequent sessions, reaching their optimal point at 2-3 months.
Are there any contraindications for polynucleotides?
There are some general contraindications for injectable treatments, such as pregnancy, lactation, active infections in the treated area, autoimmune diseases, or known allergy to any of the components. A prior medical assessment is essential to determine if it is a suitable treatment for you.
What is the difference between polynucleotides and hyaluronic acid?
Although both are injectables used in aesthetic medicine, their main function is different. Hyaluronic acid is primarily used to immediately hydrate and fill volumes or wrinkles. Polynucleotides, on the other hand, act by biostimulating the skin itself to improve its quality, elasticity, and luminosity in the long term, without adding direct volume.
