Taula de Continguts
What are Polynucleotides and how do they work?
Polynucleotides are biomolecular compounds derived from DNA, known for their ability to stimulate cellular regeneration. They work by promoting the production of collagen and elastin, improving skin hydration and elasticity.
They are not dermal fillers in the traditional sense, but rather biostimulators that work at a cellular level to restore skin health. Their application is done through microinjections in the areas to be treated, such as the face, neck, or décolletage.
At Santé Clínica Estética, our board-certified medical doctors evaluate each case to determine the suitability of this treatment. The goal is a gradual and natural improvement in skin quality.
Timeline of Effects: When are results visible?
The effects of polynucleotides are not immediate, as the skin regeneration process takes time. Generally, patients begin to notice subtle changes from 2-4 weeks post-treatment.
Continuous improvement is observed over the following months, reaching its optimal point around 2-3 months. This is due to the progressive stimulation of the body's own collagen production.
A complete cycle usually involves several sessions, spaced every 2-4 weeks, to enhance and maintain results. The number of sessions and the exact interval are defined during the medical consultation.
| Post-Treatment Phase | Observed Effects |
|---|---|
| 1-7 days | Possible mild temporary redness or swelling at injection sites. |
| 2-4 weeks | Beginning of improvement in skin hydration and radiance. Increased turgor. |
| 1-2 months | Increased skin elasticity and firmness. Subtle reduction of fine lines. |
| 2-3 months | Optimal results: more revitalized, even-toned, and better textured skin. |
| Maintenance | Booster sessions are recommended every 6-12 months, as per medical assessment. |
Realistic Expectations of the Treatment
It is essential to understand that polynucleotides aim to improve skin quality and prevent aging. They do not offer a volumizing filler effect like hyaluronic acid or relax muscles like botulinum toxin.
Results vary significantly among individuals, influenced by factors such as age, skin type, lifestyle, and the degree of initial skin damage. Naturalness is always the main objective.
«Polynucleotides are a valuable tool for biostimulation and improving dermal quality. Our patients appreciate the progressive and natural results, which integrate harmoniously into the overall appearance.»
A radical "transformation" cannot be promised, but rather healthier, firmer, and more radiant skin. Prior medical assessment is crucial for establishing clear and realistic expectations.
Who are ideal candidates?
Polynucleotides are suitable for people looking to improve their skin's texture, elasticity, and radiance. They are an excellent option for those who wish to prevent signs of aging or treat the first symptoms.
They also benefit dehydrated skin, skin lacking tone, or with small fine wrinkles. They can be a complement to other aesthetic treatments, always under medical supervision.
During the consultation, our specialists determine if this treatment aligns with your individual goals and needs. The patient's general health is an important factor in the decision-making process.
How Santé Clínica Estética approaches it
At Santé Clínica Estética, every polynucleotide treatment begins with a thorough medical assessment. Our board-certified medical doctors analyze your medical history and the specific characteristics of your skin to design a personalized protocol.
Safety and naturalness are our priorities. We use products of proven quality and precise injection techniques, performed by professionals with extensive experience.
We offer a free aesthetic consultation so you can resolve all your doubts and understand the process. Our multilingual team will assist you in Spanish, English, Portuguese, or Russian, ensuring clear and effective communication.
Post-treatment follow-up is an integral part of our service, including a review at two weeks at no additional cost. We ensure that the results are as expected and that you feel supported at all times.
Key points
- Polynucleotides are biostimulators that improve skin quality, not fillers.
- Results are progressive, visible from 2-4 weeks and optimal at 2-3 months.
- The goal is a natural improvement in skin hydration, elasticity, and radiance.
- Medical assessment is essential to establish realistic expectations and a personalized treatment plan.
- At Santé Clínica Estética, all treatments are performed by board-certified medical doctors.
Frequently asked questions
Do polynucleotides have side effects?
Side effects are usually mild and temporary, such as redness, swelling, or small bruises at the injection sites. These disappear within a few days. It is essential to follow your doctor's post-treatment instructions.
How many sessions are needed?
The number of sessions varies depending on the initial condition of the skin and the patient's goals, but generally 2-4 initial sessions spaced every 2-4 weeks are recommended. Your doctor at Santé Clínica Estética will indicate the most suitable protocol.
What is the price of a polynucleotide treatment?
At Santé Clínica Estética, the price for a facial polynucleotide treatment is 400€. We invite you to a free aesthetic consultation to get a personalized assessment and a detailed treatment plan.
Can polynucleotides be combined with other treatments?
Yes, polynucleotides can be combined with other aesthetic treatments such as hyaluronic acid, botulinum toxin, or laser, to enhance results. The sequence and type of combination will always be determined by the specialist doctor, ensuring the safety and effectiveness of the combined protocol.
- Free Aesthetic Consultation
- Personalized Medical Assessment
- Individual Protocol Design
- Polynucleotide Session 1
- 2-Week Review
- Polynucleotide Session 2 (if applicable)
- Follow-up and Maintenance

