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Skin Glow, Skin Booster, or Polynucleotides: Which to Choose?

Looking to revitalize your skin but unsure whether to choose Skin Glow, Skin Boosters, or Polynucleotides? The right choice depends on your skin's specific needs, aesthetic goals, and a medical assessment.

September 27, 2026
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Understanding Skin Revitalization

Aesthetic medicine offers various options to improve skin quality, hydration, and luminosity. Concepts like Skin Glow, Skin Boosters, and Polynucleotides refer to treatments that aim to revitalize the skin from within. Although they share the goal of healthier, more radiant skin, their mechanisms and formulations are distinct.

It's not about which is better in absolute terms, but which is most appropriate for your particular case. Every skin is unique and responds differently to active ingredients. Therefore, medical evaluation is fundamental for an informed and safe choice.

What are Skin Boosters?

Skin Boosters are injectable treatments based on non-crosslinked or lightly crosslinked hyaluronic acid. Their main objective is to deeply hydrate the skin and improve its elasticity and tone. They work by attracting and retaining water, which gives the skin a plumper appearance and a smoother texture.

They are applied through microinjections into the superficial dermis, in areas such as the face, neck, décolletage, and hands. Results are usually seen gradually, with improvements in hydration and luminosity consolidating after several sessions. They do not provide volume like traditional hyaluronic acid fillers, but rather improve the intrinsic quality of the skin.

What are Polynucleotides?

Polynucleotides are skin biostimulators derived from DNA. Their function is to stimulate cell regeneration and the natural production of collagen and elastin. This translates into improved firmness, elasticity, and tissue repair.

They are especially useful for treating mild sagging, improving skin texture, and reducing signs of aging. They can also be beneficial for the periocular area, neck, and décolletage. Their regenerative action contributes to denser, more resilient skin over time.

Skin Glow: An Approach to Luminosity

The Skin Glow treatment at Santé Clinics is designed to revitalize the skin and enhance its luminosity. This protocol aims for a "radiant skin" effect, characterized by its smoothness, uniformity, and glow. It is a comprehensive approach to restoring skin vitality.

Treatment Comparison

To facilitate understanding, we present a comparative table of the three approaches:

Characteristic Skin Boosters Polynucleotides Skin Glow
Main Active Ingredient Non-crosslinked Hyaluronic Acid Polynucleotides (DNA) Revitalization protocol
Main Mechanism Deep hydration, improved elasticity Collagen and elastin biostimulation Nutrition, luminosity, revitalization
Common Indications Dehydrated, thin skin, loss of radiance Mild sagging, loss of elasticity, texture Dull, tired skin, seeking freshness
Key Results Plump, elastic, luminous skin Firmer, denser, regenerated skin Radiant, even, youthful-looking skin
Price (approx. per session) From 250 € From 400 € 179 €

"The key in aesthetic medicine is not to follow trends, but to understand skin physiology and apply treatments with scientific rigor. Our goal is always to achieve natural results that enhance each patient's individual beauty, under the supervision of our board-certified medical team."

Key Points

  • Skin Boosters: Ideal for intense hydration and improved elasticity.
  • Polynucleotides: Focused on cell regeneration and collagen production.
  • Skin Glow: A protocol to revitalize and provide overall luminosity to the skin.
  • The choice should always be the result of a personalized medical assessment.
  • Results are gradual and aim for a natural improvement in skin quality.

How Santé Clinics Approaches This

At Santé Clinics, we understand that the decision about the most suitable treatment must always be informed and personalized. Therefore, every process begins with a thorough medical assessment. Our qualified medical doctors, such as Dr. Sol Monsalve (Medical Director), Dr. Alejandro Infante, or Dr. Lucía Peralta, analyze your skin characteristics and aesthetic goals.

During this consultation, which is free for aesthetic treatments, a personalized protocol is designed. The options, active ingredients, treatment steps, and realistic expectations are explained in detail. Our team can assist you in Spanish, English, Portuguese, and Russian, ensuring fluent and precise communication.

Patient safety is our priority. Therefore, we invest in cutting-edge technologies and ensure that all procedures are performed or supervised by qualified medical doctors. We do not promise radical transformations, but subtle and natural improvements that respect your physiognomy. Individual results may vary depending on the characteristics of each skin and adherence to post-treatment recommendations.

Frequently Asked Questions

How long do the effects of these treatments last?

The duration of effects varies depending on the treatment, skin type, and patient's lifestyle. Generally, Skin Boosters may require maintenance sessions every 6-12 months. Polynucleotides offer more lasting results due to their biostimulating action, with initial protocols and booster sessions. Skin Glow, being a protocol, adapts to individualized maintenance needs.

Are these procedures painful?

Most of these treatments are performed with very fine needles, and many patients tolerate them well. To minimize any discomfort, a topical anesthetic cream can be applied before the procedure. Our medical doctors are trained to perform injections as comfortably as possible.

Is there any recovery time or "down time"?

Generally, recovery time is minimal. Slight redness, small bumps, or minor bruising at the injection sites may appear, which usually disappear within a few hours or days. It is recommended to avoid direct sun exposure and intense exercise for the first 24-48 hours after treatment.

Can I combine these treatments with other aesthetic procedures?

Yes, in fact, combining treatments often offers more complete and synergistic results. For example, they can be complemented with neuromodulators for expression lines or with laser treatments to improve skin texture. The ideal combination will be determined during your medical consultation, adapting it to your comprehensive aesthetic plan.

What is the ideal age to start these treatments?

There is no fixed "ideal" age, as it depends on the individual needs of each skin. Young patients (from 25-30 years old) can benefit from these treatments as a preventive measure to maintain skin quality. At older ages, they help reverse and improve visible signs of skin aging. Prevention and maintenance are key at all stages.

Generalitat de Catalunya - Departament de Salut - Direcció General d'Ordenació i Regulació SanitàriaFinanciado por la Unión Europea - NextGenerationEU, Gobierno de España, ENISA, Plan de Recuperación, Transformación y Resiliencia