Table of Contents
- What happens to your body on a long flight?
- What is intravenous hydration?
- What can it offer after a trip?
- IV therapy options: comparison
- When is the result assessed?
- What is the process, step by step?
- Who is it indicated for, and when not?
- Key points
- How Santé Clinics approaches it
- Frequently asked questions
Jet lag and travel dehydration are two distinct problems that coincide: the first disrupts your internal clock and the second depletes your fluid and electrolyte reserves. Intravenous hydration delivers saline, electrolytes and vitamins directly into the bloodstream in a 30- to 60-minute session, always after a medical assessment. It is a support for the traveler's recovery, not a cure for the time-zone shift, and results vary from person to person.
What happens to your body on a long flight?
Cabin dehydration
Cabin air is dry: aviation industry data places relative humidity between 10% and 20%, lower than in many deserts. Breathing that air increases insensible water loss, and some aerospace medicine estimates put the loss at around 1.5 liters on a ten-hour flight. Alcohol and caffeine, due to their diuretic effect, worsen that negative balance.
Cabin humidity during a long-haul flight usually sits between 10% and 20%. For reference, the recommended indoor ambient humidity for respiratory comfort is between 40% and 60%.
The usual signs are dry mucous membranes, mild headache, fatigue and tight skin. In most healthy travelers it resolves with water, electrolytes and rest within 24-48 hours.
Time-zone shift: jet lag proper
Jet lag is a mismatch between your circadian rhythm and the local time at your destination. Sleep medicine uses a rule of thumb: the body needs roughly one day per time zone crossed to resynchronize. A Barcelona–New York flight, with a six-hour difference, can mean close to a week of full adaptation.
Sleep medicine rule of thumb: approximately one day of adaptation per time zone crossed. On routes of six or more time zones, full resynchronization can take a week.
The most frequent symptoms are insomnia, daytime sleepiness, difficulty concentrating and digestive discomfort. No infusion reprograms the circadian rhythm: sunlight, meal times and sleep remain the basis of adjustment.
What is intravenous hydration?
It is the administration of saline solution, electrolytes and vitamins through a peripheral venous line, usually in the forearm. By entering the circulation directly, the bioavailability of the intake is 100%, without passing through the digestive tract. At Santé it is performed by a team of licensed medical doctors, with prior clinical history and informed consent.
The vitamin session lasts between 30 and 60 minutes. NAD+ infusions require between 60 and 120 minutes due to their slower infusion rate.
What can it offer after a trip?
As recovery support, IV therapy can contribute to rehydration, to the feeling of energy and vitality, and to recovery from travel-related dehydration. The Premium Drip includes glutathione, vitamin C, B-complex vitamins, biotin and magnesium; the Fitness Drip adds carnitine, zinc and taurine, aimed at physical recovery. These uses are described as wellness support, never as a promise of results, and individual response varies.
What it cannot promise: eliminating jet lag, replacing sleep or treating an illness. If you have a fever, persistent vomiting or signs of severe dehydration, the appropriate route is urgent medical care, not an aesthetic clinic.
IV therapy options: comparison
| Formula | Main components | Session duration | Price per session |
|---|---|---|---|
| SANTÉ Premium Drip | Glutathione, vitamin C, B complex, biotin, magnesium | 30-60 min | €250 |
| Fitness Drip | Carnitine, B complex, zinc, taurine, vitamin C, biotin | 30-60 min | €250 |
| Custom Drip | Personalized after medical assessment | 30-60 min | Varies with personalization |
| NAD+ IV | NAD+ 250 mg / 500 mg / 1000 mg | 60-120 min | €500 / €750 / €1,000 |
For NAD+, courses of 4 to 6 sessions are recommended when a sustained effect is sought. The occasional traveler looking for rehydration after a flight usually considers a single vitamin session.
When is the result assessed?
The rehydration effect is assessed the same day, at the end of the session and over the following 24 hours. Recovery of sleep and concentration depends on circadian adjustment: count days, not hours, following the one-day-per-time-zone rule. If after 3-4 days fatigue persists with the same intensity, it is worth reviewing other factors with your doctor.
What is the process, step by step?
- Medical assessment
- Suitable for IV?
- Personalized protocol
- Alternatives or referral
- IV session 30-60 min
- Observation and guidance
- Follow-up
The prior medical assessment (€50) reviews your history, your medication and possible contraindications such as kidney or heart failure. If you are not a candidate, the doctor will tell you and guide you: saying no is also part of medical practice.
Who is it indicated for, and when not?
Typical profile: a healthy adult, after flights of more than 6-8 hours or trips involving time-zone changes, seeking support for rehydration and recovery. It is not indicated as a substitute for medical treatment, and the prior assessment rules out contraindications such as certain heart conditions, kidney failure or allergies to components. The most frequent adverse effects are mild and local: discomfort or a small bruise at the puncture site.
Key points
- An aircraft cabin has 10-20% humidity; fluid loss on long flights is real and measurable.
- Jet lag is corrected with light, schedules and sleep: count approximately one day per time zone.
- IV hydration delivers saline, electrolytes and vitamins with 100% bioavailability, in 30-60 minutes.
- It is recovery support, not a cure; results vary from person to person.
- Every session at Santé begins with a medical assessment and is performed by a team of licensed medical doctors.
How Santé Clinics approaches it
At Santé, IV therapy is led by Dr. Alejandro Infante and performed by a team of licensed medical doctors. Every protocol begins with a medical assessment (€50) that reviews your history and defines the formula: Premium Drip, Fitness Drip, personalized Custom Drip or NAD+ IV. The aesthetic consultation is free if you want to explore other wellness treatments during the same visit.
We see patients in Spanish, English, Portuguese and Russian, at Avenida Diagonal 384, Barcelona, Monday to Friday from 9:00 to 21:00 and weekends from 10:00 to 20:00. Prices are public and the two-week follow-up review is included at no extra cost.
Frequently asked questions
Does intravenous hydration eliminate jet lag?
No. Jet lag is a circadian rhythm mismatch that is corrected with sunlight, regular schedules and sleep, at a rate of roughly one day per time zone. IV therapy supports rehydration and the feeling of energy, and results vary from person to person.
How long does the session last, and can I carry on with my day afterwards?
Vitamin infusions last between 30 and 60 minutes; NAD+ infusions, between 60 and 120 minutes. Most people resume their normal activity the same day, with the only instruction being to care for the puncture site for a few hours.
Is it safe?
It is performed by a team of licensed medical doctors after a medical assessment that rules out contraindications. The most frequent adverse effects are mild and local, such as a small bruise at the puncture site. As with any intravenous procedure, there are infrequent risks that the doctor will explain to you before informed consent.
How many sessions do I need?
For one-off rehydration after a flight, a single session is usually enough. For NAD+ with a sustained-effect goal, courses of 4 to 6 sessions are recommended. The final regimen is defined by the medical assessment according to your case.
How much does intravenous hydration cost in Barcelona?
At Santé, the Premium Drip and the Fitness Drip cost €250 per session; the Custom Drip varies with personalization, and NAD+ IV starts at €500 (250 mg). The prior medical assessment costs €50.

