Table of Contents
What is ultrasound-guided hyaluronidase?
Hyaluronidase is an enzyme that degrades hyaluronic acid, dissolving injected fillers. When applied with ultrasound guidance, the doctor uses an ultrasound scanner to visualize the exact location of the filler and the needle in real-time. This allows for precise and controlled dissolution, minimizing impact on surrounding tissues.
This technique is essential for correcting complications or unsatisfactory aesthetic results. Direct visualization of the treatment area increases the safety of the procedure. At Santé Clínica Estética, we use it as part of our safety protocols.
Why is it necessary to correct a hyaluronic acid filler?
Although hyaluronic acid is a biocompatible and reabsorbable material, situations may arise that require its dissolution. The reasons are varied, from the appearance of nodules or asymmetries to vascular occlusion, a rare but serious complication. It is also used due to patient aesthetic dissatisfaction.
Correction with hyaluronidase allows for restoring natural anatomy or improving the aesthetic result. It is a key tool in modern aesthetic medicine. The ability to reverse a treatment increases patient confidence and safety.
Common reasons for hyaluronidase application:
- Undesired aesthetic results: Asymmetries, overcorrection, or an unnatural appearance.
- Complications: Palpable nodules, granulomas, or persistent inflammation.
- Vascular complications: Obstruction of blood vessels, which can compromise tissue irrigation.
- Change of preferences: The patient wishes to reverse the effect of the filler for personal reasons.
The role of ultrasound in procedure safety
Ultrasound has revolutionized the application of hyaluronidase by offering detailed visualization of anatomical structures. It allows the doctor to precisely identify the location of the hyaluronic acid, its depth, and its relationship with blood vessels and nerves. This information is crucial for a safe injection.
Without ultrasound guidance, hyaluronidase injection is performed blindly, which increases the risk of not reaching the filler material or affecting undesired areas. With ultrasound, control is maximized. At Santé Clínica Estética, our doctors use this technology to optimize each correction.
Benefits of ultrasound-guided hyaluronidase:
- Precision: Selective dissolution of the filler without affecting adjacent tissues.
- Safety: Minimization of injection risks into blood vessels or nerves.
- Efficacy: Higher probability of successful correction, even in complex cases.
- Less product quantity: The exact dose of hyaluronidase is used, optimizing the treatment.
- Patient comfort: Reduction of post-procedure inflammation and bruising.
The process at Santé Clínica Estética
At Santé Clínica Estética, every ultrasound-guided hyaluronidase procedure begins with a thorough medical evaluation. Our board-certified doctors analyze the patient's history and the nature of the filler to be corrected. An initial ultrasound mapping is performed to identify the material and surrounding structures.
During the procedure, the ultrasound guides the needle in real-time to the hyaluronic acid deposit. Hyaluronidase is injected directly into the material, observing its dissolution. The patient may experience a slight sensation of pressure, but the procedure is generally well-tolerated.
The results of hyaluronidase are usually visible within hours or days. However, a complete assessment is made at a follow-up consultation two weeks later, included at no additional cost. In some cases, more than one session may be necessary for complete dissolution, depending on the density and quantity of the filler.

How Santé Clinics approaches it
At Santé Clínica Estética, safety and naturalness are pillars of our philosophy. The correction of hyaluronic acid fillers using ultrasound-guided hyaluronidase is an example of our commitment to medical excellence. Our team of board-certified doctors, led by Dr. Sol Monsalve, Medical Director, is highly trained in the use of this technology.
We offer a detailed initial medical assessment for each patient. The protocol is always personalized, adapted to specific needs and facial anatomy. The aesthetic consultation is free, allowing the patient to express their concerns and receive professional guidance.
Our clinic at Avenida Diagonal 384, Barcelona, is equipped with state-of-the-art technology, such as the ultrasound scanner, to ensure maximum precision and safety. We serve patients in Spanish, English, Portuguese, and Russian, ensuring fluid communication and a trusting environment for all our patients.
Key points
- Ultrasound-guided hyaluronidase dissolves hyaluronic acid fillers with precision.
- It is used to correct asymmetries, nodules, or vascular complications.
- Ultrasound visualizes the filler and needle in real-time, increasing safety.
- At Santé Clínica Estética, the procedure is performed by board-certified doctors.
- Results are evaluated at a follow-up consultation two weeks later.
Frequently asked questions
Is the hyaluronidase procedure painful?
Generally, the procedure is well-tolerated. Topical or local anesthesia can be applied to minimize any discomfort. Some patients report a slight stinging or pressure sensation at the time of injection.
How long do results take to appear?
The effects of hyaluronidase are usually quite rapid, with a visible reduction in volume within a few hours. Complete dissolution can take between 24 and 48 hours. A final evaluation is performed at a two-week follow-up consultation to confirm the desired result.
Are there risks or side effects?
As with any medical procedure, there are risks, although ultrasound-guided hyaluronidase significantly minimizes them. Common side effects may include temporary swelling, redness, or small bruises at the injection site. Allergic reactions are rare, but a prior allergy test is performed if there is a history.
Can hyaluronic acid be reinjected after hyaluronidase?
Yes, once the original hyaluronic acid has dissolved and the area has recovered, a new filler injection can be considered. It is advisable to wait at least two weeks after hyaluronidase application to allow tissues to fully settle before any new treatment.
What is the price of ultrasound-guided hyaluronidase at Santé Clínica Estética?
The price for hyaluronidase at Santé Clínica Estética is €200 per session. This cost includes the use of ultrasound to guide the procedure and the two-week follow-up consultation. The initial medical assessment is free to evaluate your specific case.

